Rule #5: No questions about building/buying computers, hardware, peripherals, furniture, etc Those questions would be more appropriate for the game's subreddit if it exists. General game related discussion is allowed, but game-specific help requests (how to defeat a certain boss or level, what loadout is best for my character, etc) and basic questions (is a game co-op, does this game have controller support, etc) aren't. Tech support questions can be posted in our stickied tech support thread. Rule #4: No tech support or game help questions Low effort posts/comments and submissions not attempting to create discussion are prohibited. This includes contextless images/screenshots/GIFs as well as anti-platform or PCMR language such as "master race" and calling people peasants. Rule #3: No memes, PCMR language, or low-effort posts/comments No affiliate or referral links: This includes Amazon, GMG tap links, Star Citizen, etc.ĭevelopers must be verified before posting about their projects and, once they are, are not bound by rule #2. Discord, TeamSpeak), contextless website or subreddit links, and listings on eBay or other sales platforms. Rule #2: No advertisementsĪds include, but are not limited to, chat/game server & community recruitment (i.e. Please see our full rules on piracy here. Please see our full rules on self-promotion here. Rule #1: No spam, porn, or facilitating piracy No calls for violence against any groups or individuals.Īny account less than 90 days old may be permanently banned on the first infraction of this rule. No racist, sexist, homophobic, transphobic or other hateful language. This includes calling or implying another redditor is a shill or a fanboy. No personal attacks, witch-hunts, or inflammatory language. Looking for help with building or buying a PC? Check out /r/buildapc! | For all tech support questions please use the sticky! Join /r/pcgaming on Discord To check out our previous AMAs, click here. If you're a fan of Diner Dash and you haven't played the fourth installment yet (I recommend giving it a try), you need to get to it right away, since it's one of the best installments of the Diner Dash series.If you would like to schedule an AMA on /r/pcgaming please send us a message via modmail. The graphics are still nice, and the game play is still great. I'm not entirely sure why I loved it so much, since the third installment in the Diner Dash series was actually better, but I can definitely say that this is one of the best Diner Dash games to play. I don't want to give too much away, but I will say that Diner Dash: Home Town Hero delivers everything that Diner Dash fans have come to love about Diner Dash: Flo and Friends.Īfter hearing the voice of the legendary Flo Amore, Diner Dash: Home Town Hero was one of the games I downloaded right away. The fourth installment of the Diner Dash series follows Flo and her friends as they try to solve the mystery of their past, which involves traveling back in time (and back again). Diner Dash is based around the life of Flo, who is your friendly waitress at Flo and Friends diner. When you take on the task of helping Flo regain her honor by restoring her diner, you'll travel to Flo's hometown of Davenport (yes, it's named after the restaurant where you frequent. Now, let's talk about the story for Diner Dash: Home Town Hero. In fact, one of the scenes in the game looks so real that my Diner Dash buddies were like, did Flo just stare off into the distance like that, or was she really do that? The background music for the Diner Dash games is also quite nice, especially the ones that have been remixed by famous artists. The game is colorful, has plenty of graphics for the casual and really drawn-out for the hardcore Diner Dash fan. Diner Dash: Hometown Hero is a new mobile game from Diner Dash: Flo and Friends on the App Store that lets you relive the glory days of the Diner Dash diner and help Flo get back on track as she tries to run the diner and make it into a successful business.
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Compared to the traditional methods, such as invasive surgeries, radiation and chemotherapy, immunotherapy is more specific and less toxic to patients. Immunotherapy has become a revolution in the area of cancer treatment. Tumor-infiltrating Lymphocytes-based Antibody Discovery ServiceĪll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease. Screening for COVID-19 T-cell Peptides and Immune Monitoring with MHC Tetramers.Angiotensin-converting Enzyme 2 (ACE2)-CHO Cell Line Model for COVID-19. Cancer Vaccine Analytical Characterization.Induction of Antitumor Cytotoxic Lymphocytes Using Engineered Human Primary Blood Dendritic Cells.CellRapeutics™ Chimeric Engulfment Receptor (CER) Technology.CellRapeutics™ TCR/CAR/Antigen-Engineered Regulatory T Cells (Tregs).Antibody-Coupled T Cell Receptor (ACTR) Platform.NR4A Knock Out CAR-T Cell Development with CRISPR Technology.TRAC-CAR-T Cell Development with CRISPR/Cas9 Technology.Nanoparticle Tiny Tech for Programming T Cells.High-throughput Screening for T Cell Activity Modulator Discovery.Modular CAR-T Cell Generation with AAV-Cpf1.Organoid-induced Differentiation of Conventional T Cells from hPSCs.CellRapeutics™ Antibody-TCR (AbTCR) Technology.CellRapeutics™ Anti-HIV CAR Cell Therapy Development.TCR-Like CAR Construction and Evaluation Service.TCR-Like Antibody Affinity Characterization.MHC/Peptide Complex Production for TCR-Like Antibody Discovery.One-stop Cytokine Release Syndrome (CRS) Management Solutions.iPSC-derived CAR-NK Therapy Development.TCR Biomarker Identification & Selection.Replication-Competent Virus Testing Service.In this review we will retrace the history of antibodies from the times of serum therapy to modern mAbs and lay out how the current run for effective treatments against COVID-19 will lead to a quantum leap in scientific, technological and health care system innovation around mAb treatments for infectious diseases.ĬOVID-19 Innovation Monoclonal antibody mAb serum therapy.Ĭopyright © 2020 The Authors. This trend is further accelerated by ongoing or imminent health crises like COVID-19 and antimicrobial resistance (AMR), where antibodies could be the last resort. MAbs against devastating diseases like Ebola, HIV and other complex pathogens are now within reach. Vast advances in mAb isolation, engineering and production have entirely shifted the cost-efficacy balance. The development of urgently needed and highly effective mAbs as preventive and therapeutic treatments against a variety of pathogens is gaining traction. Only very few mAbs against RSV, anthrax, Clostridium difficile or rabies have reached the market. For years the high production cost and limited efficacy have blocked broader application of mAbs in the infectious disease space, which instead has been dominated for almost a century by effective and cheap antibiotics and vaccines. Instead, development of effective mAbs against infectious diseases has been lagging behind. This success is mainly driven by treatments in the oncology and autoimmune space. In recent years the global market for monoclonal antibodies (mAbs) became a multi-billion-dollar business. The entire project-covering all 26 buildings in this development-is expected to be complete within about two years. Prep work on the roof repairs here at the Queensbridge Houses begins this week. And so the best hope for improving public housing is right here at City Hall,” says Councilman Ritchie Torres. I think Albany has no interest in preserving public housing. “The $100 million is going to be controlled by the state because the state has a better track record at construction,” Cuomo says.īut despite blistering criticism from the City Council, which blasted the move at a hearing last month, there’s no sign Cuomo's had a change of heart. Roof repairs at an additional 123 buildings at 18 developments will have to wait, though that plan was rejected by Governor Andrew Cuomo, who instead wants to put $100 million in state funding toward quality of life improvements like lighting or playground equipment. Because when it rains, it literally rains in some of the tenants’ apartments,” says Queensbridge Tenant Association President April L. Firefighters are trying to ban metal roofs because. If a home is on fire and it has a metal roof, this can be a huge problem. Firefighters usually cut an access hole through the roof to enter the home. “We’re very happy, and I’m speaking for the residents, that the roofs are finally being done. This cannot be done when there is a metal roof, and, if attempted, it can cause sharp edges that can cut anyone climbing in or out of the home. At Queensbridge, among other repairs, brick parapets will be replaced with metal railing. Indeed, with the help of $100 million from the city, the housing authority is replacing dozens of roofs, an urgent need it says alleviates other problems like mold. And that’s what we’re here to do,” says NYCHA's Matt Dixon. We have patch material on masonry that shouldn’t be there. It’s most visible where the roof has "blistered,” or bubbled-water collects where it shouldn’t, seeping through the insulation and often leaking into tenants’ apartments. The roofs here are well past their useful lives, according to Housing Authority officials. It’s a great view from the roof of the Queensbridge Houses, that is, until you look down. Officials at the city's Housing Authority are moving forward with what they say are desperately needed roof repairs-but they’re doing it without the help of $100 million in state funding, money Governor Andrew Cuomo redirected away from the program last month. The member constants in basic_regex are duplicates of the syntax_option_type constants defined in the namespace std::regex_constants. The other options serve as modifiers, such that std :: regex ( "meow", std :: regex :: icase ) is equivalent to std :: regex ( "meow", std :: regex :: ECMAScript |std :: regex :: icase ). If no grammar is chosen, ECMAScript is assumed to be selected. This is effectively the same as the extended option with the addition of newline ' \n' as an alternation separator in addition to '|'.Īt most one grammar option must be chosen out of ECMAScript, basic, extended, awk, grep, egrep. Use the regular expression grammar used by the grep utility, with the -E option, in POSIX. This is effectively the same as the basic option with the addition of newline ' \n' as an alternation separator. Use the regular expression grammar used by the grep utility in POSIX. Use the regular expression grammar used by the awk utility in POSIX ( grammar documentation). Use the extended POSIX regular expression grammar ( grammar documentation). Use the basic POSIX regular expression grammar ( grammar documentation). Use the Modified ECMAScript regular expression grammar. RegExr is an online tool to learn, build, Patience is advised while gamers wait to see what new directions Paradox intends to take with the game. Imperator will likely go down the same route, but for now, it compares less favourably to its more polished predecessors. EU4 and CK2 each have had about 15 paid expansions released with more to come and are now practically different games from what they were at launch. Imperator was pretty close to what a simulationist premodern spirit-of-the-nation GSG should be like, and a combination of it and CK2s mechanics would decently represent most historical states up to the Industrial Revolution. Paradox's business model revolves around a steady stream of paid expansions that incrementally improve upon the base game of their titles. There is also far less depth to playing as a tribal nation than as Rome, which leads me to wonder if, in keeping with another distinctively Paradox tradition, a paid expansion that fleshes the game out more will be released down the road. However, Imperator's strength is also its weakness, as the focus on warfare can make gameplay feel one-dimensional, without features like the colonisation mechanics of EU4 or the character drama of CK2 to offer some contrast. This adds a layer of scouting out a potential enemy's tactics that I hadn't seen in a Paradox grand strategy game before. I was pleasantly surprised to find that I could even adjust the tactics of my armies, with the unit make-up determining a particular tactic's effectiveness. There are also different unit types, from infantry and cavalry to the more unorthodox camel and elephant units. The beautifully detailed Alps mountains are not only for show, but actually take longer to traverse for armies as they have to navigate narrow passes. Combat is a significant upgrade from what previously amounted to slamming tiny unit icons labelled with numbers against each other. 3y As I've said in another thread, I'm not confident that they're going to implement such late-game developments like Justinian's Reconquests or the Rise of Islam, but who knows. With Rome as backdrop, it meant putting every decision I wanted to make to a vote by the Senate.įactions vie for power and influence within the Senate, and I had to bear the balance of power in mind whenever I chose to appoint a character to a high political position.īut, in a nod to the Roman Empire's relentless expansion in the history books, these are ultimately sideshows to Imperator's main business of making war. Diplomacy and building your nation's infrastructure are broadly similar to EU4, while the personality-based political system from CK2 makes an appearance. I have always use self-rising flour when making biscuits and other types of quick breads like them. So when it comes to biscuit making, butter on top, lard inside ya’ll! Flour It also gives a much more tender texture to the bread. When used in biscuits it makes them nice and fluffy like a biscuit should be. Whether you choose to use lard or shortening, you will still have a delicious biscuit!) (Update: while shortening is how I grew up, lard will provide the same effect as shortening with less adverse health effects long term. Shortening is one of those keep in your pantry at all times kind of ingredients and Crisco has always been what my family uses. Shortening is 100% fat while butter remains around that 80% mark. I have always used shortening with my biscuits instead of butter. These pantry staples are also relatively inexpensive! Fat Is Where It’s At Before we talk about how to make them, you need to know what you need to make them!īiscuit Ingredients- Simple and Wonderful The Ingredientsīiscuits are a super simple quick bread that take just three ingredients to make the perfect bread to fill your basket at dinner time. Over the years I have learned that same method, but have broken down that method into some measurements for you to be able to follow and replicate these delicious biscuits. The crazy thing is that their biscuits always turned out perfect! They always just dumped and scooped and felt until they thought it was right. I never had an exact biscuit recipe from my momma or my mawmaw. Breakfast, lunch, or dinner you will want these to be at your kitchen table. That is why these southern beauties are so wonderful! They require so very little to make and you can dress them up in so many ways. It has to reach a certain height after baking before I will qualify it as a perfect biscuit. The perfect biscuit in my opinion is soft and fluffy with the perfect balance of salt and fat. Now that we are grown and out of the house she gets to keep her funky biscuits all to herself, at least until we come to visit.įunky Southern Biscuit The Perfect Biscuit Momma rarely kept it for herself because she is a selfless woman, so instead my sister and I would fight over who got the biscuit. Honestly, they didn’t taste any different, but we all swore they were the best. I can remember these being the prized possession in the kitchen. These “funky biscuits” are reserved for the baker. You don’t quite have enough to make a perfectly round biscuit so you take the cuttings and smush them into what my momma calls a “funky biscuit” (she grew up in the 70’s folks). That was because Momma always made a bakers biscuit or two. My Momma would also let me make scrap biscuits, but Momma never quite left as many scraps Mawmaw did (I think Mawmaw did that on purpose). It fills my heart with so much joy to see him so excited and to remember my Mawmaw letting me do the same thing. He is always so proud of himself when we lay the thin pieces of overworked biscuit dough out onto the baking pan, and like his momma he thinks they are the best “biscuits” in the world. Any time he sees me reaching for my rolling pin, he runs into the kitchen asking to make biscuits with me. Grayson and Gunner both love to cook with me, but Grayson loves to bake. Now as a momma I let me boys do the same thing. An no matter how gross it may have tasted, I thought they were the best “biscuits” ever made. Let’s be clear, what I created was more like a cracker that was the size of a quarter and flatter than a flitter but I was always so proud when she let me bake it up in my own little pan in the big girl oven. My grandma, or Mawmaw as I always called her would let me take the little scrapes of dough that were left over from the dough on her hands and pieces that she couldn’t form into a real biscuit and would let me make my own biscuits. I can remember my momma and grandma making biscuits when I was a little girl. Both have spent more than 15 years of experience servicing the retail and commercial hardscape industry at Pioneer Landscaping Materials. Call us or stop by for your Landscape, Garden & Hydroponic product and service needs. Regional Managers Matt Hulsey and Troy McDaniel will oversee local operations for the Ewing Hardscape Supply stores in Colorado and Arizona, respectively. He became a hardscape consultant for Ewing in 2017. Prior to working at Pioneer, Sawyers was a general contractor in Colorado Springs, Colo. He’s managed hardscape supply locations and quarries at his previous position as vice president and general manager of Pioneer Landscaping Materials. Sawyers has more than 30 years of experience in the hardscape and landscape industry. Contractor customers can also order Ewing Hardscape Supply products from Ewing Irrigation locations.Ĭurrently, there are four Ewing Hardscape Supply locations:Įwing Hardscape Supply General Manager Dave Sawyers will lead the Arizona and Colorado locations. It’s diversified our business portfolio, allowing us to expand vertically and engage with a new customer segment.”Įwing Hardscape Supply will also provide in-store shopping, same or next-day delivery and well-stocked inventory, said the company. Landscaping Supply Store 26 suppliers on in Phoenix: Crystal, Leave, Grand Products Companies Distributors Dealers Contact. “This dedicated hardscape division was a natural next step for us. SiteOne Landscape Supply Back to Branch Locator Ask an Expert Closed (623)-587-5636 22010 N 21st Ave Phoenix, AZ 85027-2004 Monday 6:00 a.m.- 4:00 p.m. Medical, Dental and Vision plans Paid Time Off, Paid. “Our new Ewing Hardscape Supply locations showcase the strength of Ewing as a green industry leader,” said Douglas W. SiteOne Landscape Supply is the largest and only national wholesale distributor of landscaping. This new sector offers contractors greater access to bulk material, including decorative rock, boulders and riprap, flagstone, river rock, sand, topsoil, soil mixes and mulch, as well as pavers, travertine, wall blocks, building material, lighting, grills and fire pits, artificial grass, tools and accessories. Pinnacle Peak store in North Phoenix, Ariz.Įwing Irrigation & Landscape Supply opened its first Ewing Hardscape Supply locations in Arizona and Colorado. The shoebill resembles a stork in its structure and shape, and this is why it is also sometimes referred to as the shoebill stork. The shoebill is very closely related to pelicans, which is why it is sometimes referred to as a shoebill pelican and is classified in the order Pelecaniformes. However, in the past, the shoebill was miscategorized as belonging to the Ciconiiformes order, which includes storks.
That gave the Blazers a narrow four point lead with 8:25 to go. A Greg Brown III drive and dunk in heavy traffic also earned him a foul shot, which he duly converted. Intensity stayed dialed up for both teams, especially on the defensive end. The quarter ended 92-90 and set up a must-see fourth quarter. Both teams dialed up the aggressiveness on defense, but neither team could take control. Utah, angered at the no-call, got called for a technical foul as well. The game was starting to get a bit frantic, and a few turnovers started to creep into the Blazers’ nearly pristine stat sheet.Īn uncalled Nurkic foul stymied the Jazz on one end and led to a fast break for the Blazers. Simons led the rearguard action, but the Jazz continued on the front foot and were able to take the lead with 6:42 remaining in the quarter. Things didn’t get much better after the timeout. Vanderbilt, a career 25.6% shooter from three, was 4-4 behind the arc, perhaps giving Chauncey second thoughts about the apparent strategy of leaving him completely alone in the corner. A deep ball from Kelly Olynyk and another from Jared Vanderbilt forced a quick timeout from the Blazers with the lead cut to 4 at 71-67. The Blazers came out of the half a bit lethargic and Utah took advantage. It was a pleasing half of basketball for Portland, with the only negative thought being that the team probably feeling that they should be up by more. As it was he finished the half with 33 and the Blazers led by nine, 69-60. That’s what they did, but unfortunately the refs swallowed their whistles in dubious circumstances or Ant might have gone for 40 in the half. The only way the Jazz could stop him was to foul him. After a number of possessions with Simons not getting any looks, the Blazers put Anfernee off the ball and things started to open up for him. One of the biggest reasons is that the first Portland turnover of the evening came with 5:31 left in the second quarter. The Jazz huffed and puffed, but the Blazers did a a good job of keeping them largely at arm’s length. By the time Utah called timeout with 7:32 left in the quarter the Blazers had the lead back up to 11. A third foul forced him to the bench a bit early, but not before collecting three rebounds and four points and touching the ball pretty much every time down the court. Shaedon Sharpe seemed to be involved in every play, sometimes in a good way and sometimes not so much. Utah got off to a fast start and cut the lead to five, but the Blazers fought back by driving at Jazz big men and demonstrating stout defense. Simons finished the quarter with a stupendous 23 points, while no other player for either team could achieve double figures. The Jazz were able to whittle away at the lead slightly, but a buzzer-beater circus shot by the man of the hour, Simons, meant that the quarter ended with the Blazers enjoying a 40-31 lead. What’s that I hear? Is that Anfernee Simon’s music? Three Ant makes from deep only broken up by a Jusuf Nurkic putback and suddenly Portland led by 10 as they went to commercial. They spent the next few minutes trading baskets, turnovers, and threes. Then the teams decided that imitation is the best form of flattery. Markkanen came out of the timeout and promptly drilled a three and shortly after got fouled on another, giving him the opportunity to drain three shots from the charity stripe, which he converted. The Blazers’ defense was active, forcing two early turnovers, and Portland took advantage of them with two successful fast breaks. The Jazz countered with the three ball, but nevertheless Portland jumped out to a five-point lead, forcing a Utah timeout with 9:57 left in the quarter. The Blazers got off to a fast start, scoring on their first six possessions. After having zero in the first quarter, they finished with 20, many of which could have been potential back-breakers had things gone slightly differently. In spite of the result, the Blazers will be disappointed with their second-half turnovers. The Jazz were led by Jordan Clarkson with 24 and Lauri Markkanen with 21. Jerami Grant poured in 33 in another all-star caliber performance. Simons finished with 45 despite only scoring two in the fourth quarter. In a very exciting and hard-fought game the Blazers emerged victorious by the score of 116-111. The Utah Jazz meanwhile had won their last two, beating the Los Angeles Clippers and the Blazers’ next opponent, the Indiana Pacers. The Portland Trail Blazers came into Salt Lake City losers of seven of their last eight and looking to stop the bleeding. Holding Alt lets you see everything that's open and allows you to Tab to any program. How often do you find yourself switching between programs by clicking on their taskbar icons? Using Alt + Tab is faster as it lets you instantly switch between your last two opened applications. Type anything in and you can use Enter to snap to the next result Shift + Enter will go back one hit. When you're stuck searching for a word in a huge PDF document, web page, or other application, Ctrl + F will open the Find bar. Alternatively, Ctrl + W will also close your tab. Try ALT + F4 to close any window (identical to clicking the X in the top-right corner) or Ctrl + F4 to close out just the current tab. We'll talk about using shortcuts to open programs in Windows, but you can just as easily close out of your work with a few taps. Keeping in the Ctrl family, Ctrl + P is the universal command to print. In Word it's F12 many other programs use Ctrl + Shift + S.Ĭtrl + O will open a file into whatever program you're using. The keyboard shortcut for Save As (saving a file with a new name) depends on the app you're using. Use Ctrl + S to save whatever file you're working on-and do it often so you don't lose your work! In a browser, you can also use this to save a page for offline viewing. This also works with Ctrl + Del to delete one word in front of the cursor. When typing, instead of using Backspace to delete one character at a time, use Ctrl + Backspace to delete entire words at once. Use these two regularly and your mistakes will disappear in an instant! Its counterpart, Ctrl + Y, will redo a previously undone action. Manually dragging the mouse over the selection is much slower.Ĭtrl + Z will undo any action and is your best friend when doing any sort of work on your computer, especially tasks prone to errors such as image editing or formatting a document. Selecting all is most useful when you're trying to work with a bunch of files at once, or perhaps to grab everything you've just typed and re-use it elsewhere. Remember that no two keyboards are the same some laptop keyboards may have Function (FN) keys that perform their own functions on the F1-F12 keys.Left, Right, Up, and Down refer to the arrow keys.We'll make a note when this applies to a shortcut. For example, Space will jump down a set amount on a web page, so Shift + Space will move back up that same amount. The Shift key is used as a "reverse" function for many key combinations.If you don't find these helpful, glaze over them! As we go, we'll share various strategies for committing shortcuts to memory, including subliminally bolding letters of commands that match their shortcuts.Combinations that need to be pressed one after another will use a greater than symbol (e.g. Keyboard shortcuts that need to be pressed at the same time will use a plus symbol (e.g.All keys and combinations appear in bold.The keys on a keyboard shouldn't cause any ambiguity, but just for the sake of consistency: To be clear, this guide is written for Windows keyboards. If you never play music on your computer, you're not going to use fast-forward shortcuts, so skip those! Keep in mind that not every shortcut is worth using for every person, either. Once you're not even thinking about them anymore, add a few more to your repertoire, and keep the cycle going! Focusing on just a few common shortcuts and integrating them into your daily use will soon make them second nature. Don't worry if your memory isn't capable of remembering hundreds of shortcuts. If you were writing a paper in Word and took ten seconds to save the document every five minutes by manually clicking File > Save, you'd be spending two minutes of every hour just saving! A quick tap of Ctrl + S takes a fraction of a second and doesn't take your hands (and mind) away from typing like using the mouse does. Keeping that other hand on the keyboard and learning some keyboard shortcuts is an excellent idea your spare hand probably isn't doing anything else productive! You probably only have one hand on your mouse. Yet a mouse isn't required to use your computer at all you could get around with just a keyboard if you had to. After all, you can use your mouse to make selections, work with the toolbar options (like File, Edit, and Tools), launch programs, and navigate websites. If you're not accustomed to using them, keyboard shortcuts might seem like a waste of time. |
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